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Modern brain imaging is revolutionizing the study of brain function in health and disease. However, few realize that its origins began in the nineteenth century with Dr. Angelo Mosso's pioneering experiments.
A foremost Italian physiologist and scientist, Angelo Mosso studied several patients brought to him with head injuries that exposed their live brains to direct, long-term observation. He took advantage of these rare opportunities to document, for the first time, changes in cerebral blood flow in response to different stimuli, behaviors, and emotions, the very same changes that are now the basis for the measurements underlying modern functional brain imaging.
Mosso was widely recognized by his contemporaries for his highly original studies, published both in Italian in 1878 and in German in 1881. Yet there has never been a translation through which this groundbreaking work could be appreciated by the English-speaking world. Indeed, Angelo Mosso's sophisticated experiments were to neuroscience what surgeon William Beaumont's in vivo observations were to gastric physiology fifty years earlier. This unique monograph establishes Mosso's rightful role as the pioneer of brain imaging. Through it, the modern reader, whether expert neuroscientist or interested student, can gain a new perspective on the author's remarkable insights: how behaviors as subtle as thinking about a subject or feeling an emotion produce the changes in pulsations of the brain that he observed and recorded for posterity.
Special features of this volume include first a brief summary of Mosso's life. Two pioneers of modern brain imaging, Marcus E. Raichle (winner of the Kavli Prize for Neuroscience) and Gordon M. Shepherd (Yale University Professor of Neurobiology) then review Mosso's work and provide extensive commentary to explain its relevance to modern brain science. The authors not only emphasize Mosso's pioneering role in brain imaging, but also his fundamental contribution to the rise of cognitive neuroscience. The English translation (by historian of medicine Christiane Nockels Fabbri) follows, together with all of the plates and illustrations of the original volume. The result is a classic of neuroscience, now available for wide appreciation by neuroscientists, neurologists, psychologists, psychiatrists, historians of science and medicine, and the general public.
- Sales Rank: #2970544 in Books
- Published on: 2014-10-15
- Original language: English
- Number of items: 1
- Dimensions: 6.40" h x .80" w x 9.40" l, .0 pounds
- Binding: Hardcover
- 240 pages
Review
"How Antonio Mosso, an almost forgotten contributor to neuroimaging, was able to image brain activity without computers or MRI or any of the historical progression leading to modern methods beautifully traced in this volume, but instead with a simple recording device of his own design, will be extremely valuable to readers interested in how brain activity supports the mind. The editors are to be congratulated for bringing this important story to the English reading world."--Michael I. Posner, PhD, Professor Emeritus, Psychology , University of Oregon, Eugene, OR
"This pioneering investigation is at last available in English thanks to the masterful edition of Mosso's book by Gordon M. Shepherd and Marcus E. Raichle. This reading will be certainly inspiring for neuroscientists, psychologists and historians of science." --Paolo Mazzarello, MD, PhD, Professor of History of Medicine, University of Pavia, Pavia, Italy
"Science is a conversation that spans centuries. In his Critical Historical Introduction, Mosso summarizes the contributions of his conceptual predecessors going back to Galen. In their Introduction, Raichle and Shepherd recount the conversation from Mosso to the present day. Jointly, a thoroughly scholarly, highly-entertaining account of the evolution of functional neuroimaging." --Peter T. Fox, M.D., Director, Research Imaging Institute, Malcolm Jones Professor of Radiology, Professor of Radiology, Neurology, Psychiatry, and Physiology, University of Texas Health Science Center at San Antonio, CA
"This unique work stands alone in terms of value and placing Mosso in historical perspective as the inventor of the plethysmograph and as a researcher who measured the relationship between emotion and brain activity." --Doody's Health Sciences Book Review
Featured in the Milan Daily "Il Sole 24 ore".
"This fascinating manuscript illuminates the thought process of a brilliant scientist and forerunner of modern neuroscience. In rescuing Mosso from oblivion, Fabbri, Raichle and Shepherd have given historians, students and neuroscientists a valuable new resource to fill gaps in the narrative that modern neuroscience was built upon. Moreover, the works of Mosso give us a new perspective on age old questions of the mind and perhaps pause to appreciate the new age of wonder we live in and to attack these questions with renewed vigor and greater humility." --Studies in History and Philosophy of Biological and Biomedical Sciences
About the Author
Marcus E. Raichle, MD, PhD, Depts of Radiology, Neurology, Anatomy and Neurobiology, Washington University School of Medicine
Gordon M. Shepherd, MD, DPhil, Department of Neurobiology, Yale University Medical School
Most helpful customer reviews
2 of 2 people found the following review helpful.
A medical history book at its best
By High Words
A very special book. It highlights the 2014 first-ever English translation of Italian physiologist Angelo Mossos's book on his brain research from the 19th century, with editing and commentary on the advance of the technology of brain imaging since that time.
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